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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Venetoclax confers synthetic lethality to chidamide in preclinical models with transformed follicular lymphoma

Fig. 5

Z-VAD-FMK effectively delayed the apoptosis of venetoclax and chidamide in t-FL cells. A DOHH2, B SU-DHL-4, C RL, and D SC-1 cells were pretreated with 100 μM pan-caspase inhibitor Z-VAD-FMK for 2 h and treated with the indicated concentrations of ABT199, CS055, and the combination of the two drugs for 24 h. Data were represented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 and ns (not significant) by unpaired t test

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Clinical Epigenetics

ISSN: 1868-7083

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