Fig. 6

Validation of candidate genes associated with heart failure. A Feature plots of expression distribution for selected genes through Single cell RNA-sequencing (ScRNA-seq) analysis of the human heart cells. BÂ Methylation levels in the promoter regions of the candidate genes. CÂ RT-qPCR validation of the mRNA expression levels in Recipient and Donor groups. DÂ Top20 identified transcription factors within the promoter regions of candidate genes using HOMER. EÂ Candidate transcription factors associated with DCM-HF