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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure

Fig. 2

RNA-sequencing analysis of atrial tissues from the Donor and Recipient groups. A General workflow used in this study. B Principal Component Analysis (PCA) of mRNA expression profiles in the hearts of donors and recipients. C Volcano plots depicting the distribution of differentially expressed genes (DEGs). D Heatmaps of 681 DEGs with |log2FC|> 1 and FDR < 0.05. (E) Gene Set Enrichment Analysis (GSEA) of expressed genes in Recipient versus Donor. F-G Kyoto Encyclopedia of Genes and Genomes (KEGG) (F, upper) and Gene Ontology (GO)-Biological Process (BP) enrichment (G, lower) of the significantly up- and downregulated DEGs

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Clinical Epigenetics

ISSN: 1868-7083

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