Table 1 Proportions of the different genotypes associated with nc886 RNA levels, proportions of the nc886 methylation status groups and the proportions of the combinations of these in the cohorts utilised in the study
From: Regulation of nc886 (vtRNA2-1) RNAs is associated with cardiometabolic risk factors and diseases
YFS 2007; n = 1497; 30–45 y | DILGOM; n = 504; 25–74 y | LURIC; n = 2183; 17–92 y | KORA F4; n = 1653; 32–81 y | KORA FF4; n = 1771; 38–87 y | Bogalusa; n = 658; 36–57 y | NFBC1966; n = 792; 43–47 y | ||
|---|---|---|---|---|---|---|---|---|
nc886 methylation | ||||||||
Imprinted | 73.20% | 72.20% | 72.00% | 76.50% | 75.10% | 71.60% | 71.80% | |
Intermethylated | 3.20% | 6.30% | 4.10% | 2.60% | 3.10% | 3.40% | 3.20% | |
Nonmethylated | 23.60% | 21.40% | 23.90% | 20.90% | 21.70% | 24.80% | 25.00% | |
Genotype | ||||||||
T/T | 81.60% | 85.40% | 85.10% | 86.80% | 86.50% | 85.40% | 83.10% | |
T/C | 17.40% | 14.00% | 14.50% | 12.70% | 12.70% | 14.00% | 16.10% | |
C/C | 1.00% | 0.40% | 0.40% | 0.50% | 0.70% | 0.40% | 0.80% | |
Proxy group | ||||||||
Imprinted T/T | 59.90% | 57.90% | 61.30% | 66.20% | 64.90% | 60.90% | 59.50% | 59,50% |
Intermethylated T/T | 2.80% | 5.90% | 3.60% | 2.20% | 2.60% | 2.70% | 2.80% | 2,80% |
Nonmethylated T/T | 18.90% | 18.40% | 20.20% | 18.40% | 19.00% | 21.80% | 20.80% | 20,80% |
Imprinted T/C | 12.60% | 13.70% | 10.40% | 9.90% | 9.70% | 10.30% | 12.00% | 12,00% |
Intermethylated T/C | 0.40% | 0.40% | 0.50% | 0.40% | 0.50% | 0.70% | 0.40% | 0,40% |
Nonmethylated T/C | 4.40% | 3.00% | 3.60% | 2.40% | 2.50% | 3.00% | 3.60% | 3,60% |
Imprinted C/C | 0.70% | 0.60% | 0.30% | 0.40% | 0.50% | 0.40% | 0.30% | 0,30% |
Intermethylated C/C | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
Nonmethylated C/C | 0.30% | 0.00% | 0.10% | 0.10% | 0.20% | 0.00% | 0.60% | 0,60% |
Use in proxy | ||||||||
Control | 59.90% | 57.90% | 61.30% | 66.20% | 64.90% | 60.90% | 59.50% | |
Elevated nc886 RNA | 24.30% | 22.00% | 24.20% | 21.30% | 22.20% | 25.20% | 25.30% | |
Excluded | 15.80% | 20.00% | 14.50% | 12.50% | 12.80% | 13.70% | 15.20% | |