Table 1 Basic characteristics of participating studiesa
Study | Chip | N (% female) | Self-reported race and ethnicity | Age (years) | HDL-c (mg/dL) | LDL-c (mg/dL) | TC (mg/dL) | TG (mg/dL) b |
|---|---|---|---|---|---|---|---|---|
Discovery studies | ||||||||
ARIC | 450Â k | 1090 (58.5) | White | 60.4 (5.4) | 52.0 (18.2) | 130.5 (36.8) | 210.6 (38.6) | 4.8 (0.5) |
| Â | Â | 2274 (62.7) | African American | 57.4 (5.9) | 53.1 (17.8) | 134.5 (40.5) | 211.1 (42.4) | 4.6 (0.5) |
WHI | 450Â k | 2674 (100) | White | 69.9 (9.5) | 56.0 (14.8) | 144.4 (36.2) | 230.5 (39.5) | 4.9 (0.5) |
| Â | Â | 1451 (100) | African American | 65.2 (8.8) | 56.8 (14.8) | 147.5 (43.6) | 227.8 (46.6) | 4.7 (0.4) |
| Â | Â | 712 (100) | Hispanic/Latino | 61.5 (6.6) | 52.7 (14.1) | 140.6 (38.0) | 226.4 (42.1) | 5.0 (0.5) |
| Â | Â | 125 (100) | Asian American | 65.4 (7.1) | 60.1 (14.2) | 125.0 (31.8) | 219.7 (35.5) | 5.0 (0.5) |
| Â | Â | 48 (100) | Native American | 64.0 (7.9) | 54.2 (15.4) | 134.0 (36.3) | 222.5 (41.5) | 5.0 (0.5) |
JHS | EPIC | 1187 (61.7) | African American | 56.9 (11.6) | 51.3 (14.7) | 134.9 (34.6) | 208.0 (43.0) | 4.6 (0.5) |
Replication studies | ||||||||
Amish | 450Â k | 346 (53.0) | White | 57.1 (13.6) | 56.1 (14.6) | 145.8 (43.5) | 219.5 (48.0) | 4.3 (0.5) |
CHS | 450Â k | 419 (60.1) | White | 75.0 (4.9) | 52.4 (14.4) | 121.6 (32.8) | 204.4 (38.5) | 4.9 (0.5) |
| Â | Â | 324 (70.8) | African American | 73.1 (5.5) | 57.4 (15.5) | 122.2 (35.3) | 202.1 (39.1) | 4.6 (0.5) |
GENOA | EPIC | 943 (71.6) | African American | 57.5 (10.3) | 54.8 (16.8) | 123.8 (42.0) | 206.9 (45.7) | 4.9 (0.4) |
MEC | EPIC | 67 (67.2) | African American | 65.0 (7.1) | 46.8 (19.0) | 141.2 (41.7) | 208.7 (45.6) | 4.6 (0.5) |
| Â | Â | 91 (41.8) | Hispanic/Latino | 67.0 (6.6) | 41.7 (14.0) | 130.9 (37.6) | 205.7 (44.0) | 5.0 (0.5) |
| Â | Â | 34 (23.5) | Asian American | 63.0 (7.5) | 43.2 (18.7) | 112.3 (48.2) | 184.0 (50.3) | 4.8 (0.6) |
| Â | Â | 57 (50.9) | American Indian | 64.4 (6.3) | 40.1 (13.4) | 126.8 (39.8) | 188.9 (42.3) | 4.6 (0.5) |
MESA | EPIC | 395 (50.0) | White | 61.0 (9.9) | 51.2 (14.7) | 128.1 (30.5) | 208.0 (36.9) | 4.8 (0.5) |
| Â | Â | 181 (58.0) | African American | 61.0 (9.6) | 51.6 (14.8) | 122.7 (37.5) | 195.1 (42.5) | 4.5 (0.5) |
| Â | Â | 287 (55.0) | Hispanic/Latino | 58.6 (9.4) | 47.6 (12.2) | 125.2 (34.9) | 202.8 (39.6) | 4.9 (0.5) |
| Â | Â | 71 (46.0) | Asian American | 60.8 (10.1) | 48.4 (11.8) | 129.1 (11.8) | 211.4 (41.9) | 5.0 (0.6) |