Table 2 Twenty-seven differentially methylated CpGs (FDR < 0.05) from the meta-analysis of maternal asthma during pregnancy in relation to newborn methylation
CpG Name | Chr | Pos | UCSC Gene | UCSC group | Relation to CpG Island | Direction | Effect | SE | HetISq (%) | P value | FDR P value | Chip |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
cg26963854 | 14 | 95,902,398 |  |  | S_Shelf |  +  + − +  +  +  +  | 0.0032042 | 0.0006041 | 37 | 1.13E-07 | 4.78E-02 | 450 K |
cg08408040 | 7 | 11,381,133 |  |  | OpenSea |  − − |  − 0.0806398 | 0.0127099 | 75.4 | 2.23E-10 | 7.06E-05 | EPIC |
cg05760515 | 8 | 93,044,577 | RUNX1T1 | Body;5’UTR | OpenSea |  +  +  | 0.0035094 | 0.0006397 | 0 | 4.11E-08 | 6.50E-03 | EPIC |
cg16664062 | 22 | 43,090,408 | A4GALT | 5’UTR | S_Shore |  +  +  | 0.0104421 | 0.0020266 | 16.3 | 2.57E-07 | 2.44E-02 | EPIC |
cg01344764 | 11 | 31,979,230 |  |  | OpenSea |  − − |  − 0.0132207 | 0.0026012 | 0 | 3.73E-07 | 2.44E-02 | EPIC |
cg06909301 | 17 | 71,593,664 | SDK2 | Body | OpenSea |  −  +  |  − 0.003653 | 0.0007218 | 0 | 4.18E-07 | 2.44E-02 | EPIC |
cg01093036 | 10 | 104,489,529 | SFXN2 | Body | OpenSea |  +  +  | 0.0087239 | 0.0017305 | 0 | 4.62E-07 | 2.44E-02 | EPIC |
cg00640622 | 2 | 144,020,044 | ARHGAP15 | Body | OpenSea |  −  +  |  − 0.0163449 | 0.0032839 | 79.2 | 6.45E-07 | 2.73E-02 | EPIC |
cg20264088 | 15 | 41,166,515 | RHOV | TSS200 | Island |  +  +  | 0.0313048 | 0.0063805 | 40.4 | 9.28E-07 | 2.73E-02 | EPIC |
cg27290786 | 17 | 77,891,951 | LOC101928738; LOC101928766 | TSS1500;Body | OpenSea |  +  +  | 0.0079921 | 0.0016307 | 0 | 9.53E-07 | 2.73E-02 | EPIC |
cg15066822 | 13 | 52,352,312 | DHRS12 | Body | OpenSea |  +  +  | 0.0042652 | 0.0008708 | 0 | 9.68E-07 | 2.73E-02 | EPIC |
cg01573661 | 12 | 21,819,734 |  |  | OpenSea |  − − |  − 0.0137664 | 0.0028247 | 36.8 | 1.10E-06 | 2.73E-02 | EPIC |
cg09103231 | 2 | 73,182,547 | SFXN5 | Body | OpenSea |  +  −  | 0.0064028 | 0.0013143 | 29 | 1.11E-06 | 2.73E-02 | EPIC |
cg15075638 | 4 | 47,814,806 | CORIN | Body | OpenSea |  − − |  − 0.0050016 | 0.0010327 | 0 | 1.28E-06 | 2.73E-02 | EPIC |
cg03443357 | 5 | 14,168,374 | TRIO | Body | OpenSea |  − − |  − 0.0108232 | 0.0022411 | 0 | 1.37E-06 | 2.73E-02 | EPIC |
cg02603747 | 6 | 166,460,087 |  |  | OpenSea |  − − |  − 0.0149353 | 0.0030951 | 0 | 1.40E-06 | 2.73E-02 | EPIC |
cg16446317 | 17 | 77,490,891 | RBFOX3 | 5’UTR | OpenSea |  +  +  | 0.0062025 | 0.0012861 | 0 | 1.42E-06 | 2.73E-02 | EPIC |
cg05590737 | 19 | 10,829,803 | DNM2 | Body | S_Shore |  − − |  − 0.0187622 | 0.0038958 | 0 | 1.47E-06 | 2.73E-02 | EPIC |
cg13974400 | 2 | 179,637,873 | TTN | Body | OpenSea |  +  +  | 0.0023148 | 0.0004844 | 0 | 1.76E-06 | 3.01E-02 | EPIC |
cg10678257 | 8 | 56,987,912 | SNORD54;RPS20 | TSS1500 | S_Shore |  − − |  − 0.0061053 | 0.0012789 | 0 | 1.81E-06 | 3.01E-02 | EPIC |
cg16835843 | 21 | 45,363,997 | AGPAT3 | 5’UTR | S_Shore |  +  +  | 0.0085476 | 0.0018086 | 0 | 2.29E-06 | 3.62E-02 | EPIC |
cg20700171 | 6 | 46,729,036 |  |  | OpenSea |  − − |  − 0.0044141 | 0.0009398 | 0 | 2.65E-06 | 3.89E-02 | EPIC |
cg18940887 | 8 | 62,800,933 |  |  | OpenSea |  − − |  − 0.0076541 | 0.0016314 | 20.7 | 2.71E-06 | 3.89E-02 | EPIC |
cg04356230 | 6 | 143,251,273 | HIVEP2 | 5’UTR | S_Shelf |  − − |  − 0.0188473 | 0.0040371 | 7.4 | 3.03E-06 | 4.17E-02 | EPIC |
cg05492840 | 1 | 8,254,431 |  |  | OpenSea |  − − |  − 0.0170443 | 0.0036632 | 0 | 3.28E-06 | 4.26E-02 | EPIC |
cg09724019 | 14 | 35,192,414 |  |  | OpenSea |  − − |  − 0.0172851 | 0.0037194 | 36.2 | 3.36E-06 | 4.26E-02 | EPIC |
cg00128361 | 22 | 38,245,362 | EIF3L | TSS200 | Island |  − − |  − 0.0024848 | 0.000539 | 0 | 4.04E-06 | 4,91E-02 | EPIC |