Fig. 5
From: The effect of 1,25(OH)2D3 on Dickkopf-1 methylation in colorectal cancer

1,25(OH)2D3 upregulated DKK1 expression by inducing DKK1 demethylation. A 1,25(OH)2D3 induced DKK1 mRNA expression in SW480, DLD1 and RKO cells. B Pyrosequencing regions of DKK1 in this study. C The transcriptional activity of the differentially methylated DKK1 promoter and exon region. *p < 0.05