Fig. 4

MR sensitivity analysis of the causal relationship between DrnkWk and prolonged QT intervals. A Leave-one-out analysis identifying the effect of individual variables on the total effect. B Funnel plot showing the results of the heterogeneity analysis of the instrumental variable (IV) for causal estimation; C MR-RAPS diagnostic plots of the association between DrnkWk and QT interval prolongation, including residual plots showing the IV weights versus the standardized residuals and Q-Q plots assessing normality