Epigenome-wide analysis reveals potential biomarkers for radiation-induced toxicity risk in prostate cancer

Clinical Epigenetics

Table 3 Significant DMRs Associated with Late Severe GI and GU Adverse Effects

Chr	Start^a	End^a	width (bp)	n^o.CpGs	Gene region	p-value^b	Overlapping genes
chr11	131,630,464	131,630,648	185	3	1st exon	0.002	NTM^c
chr17	7,253,189	7,254,443	1255	10	19th, 20th, 21st exon–intron	0.006	ACAP1^d
chr2	102,803,738	102,803,787	50	3	1st exon	0.015	IL1RL2^c
chr13	23,309,689	23,310,675	987	10	IR	0.018	–^c
chr7	55,516,724	55,516,872	149	3	2nd intron	0.023	VOPP1^c
chr10	4,867,773	4,868,398	626	11	promotor + 1st exon	0.032	AKR1E2^c

ISSN: 1868-7083