Table 3 Crude and adjusted associations between protein EpiScores and overall mortality in SATSA
Model 1- crude models (n = 374) | Model 2- adjusted models (n = 374) | ||||
|---|---|---|---|---|---|
Hazard ratio* (95% CI) | Harrell’s C-index | Hazard ratio* (95% CI) | Harrell’s C-index | Corrected p-value | |
Protein EpiScores considered risk factor | |||||
IGFBP4 | 1.25 (1.10–1.43) | 0.61 | 1.23 (1.07–1.41) | 0.65 | 0.03 |
MMP9 | 1.34 (1.17–1.52) | 0.64 | 1.23 (1.06–1.42) | 0.66 | 0.05 |
OSM | 1.40 (1.23–1.59) | 0.62 | 1.32 (1.14–1.51) | 0.65 | < 0.01 |
PIGR | 1.41 (1.23–1.63) | 0.64 | 1.31 (1.10–1.56) | 0.66 | 0.03 |
RARRES2 | 1.20 (1.06–1.35) | 0.61 | 1.21 (1.07–1.38) | 0.65 | 0.03 |
S100A12 | 1.24 (1.11–1.39) | 0.60 | 1.21 (1.07–1.36) | 0.64 | 0.03 |
STC1 | 1.43 (1.17–1.73) | 0.61 | 1.48 (1.22–1.80) | 0.65 | < 0.01 |
TGFA | 1.40 (1.23–1.60) | 0.64 | 1.31 (1.14–1.51) | 0.66 | < 0.01 |
THBS2 | 1.22 (1.08–1.38) | 0.61 | 1.18 (1.05–1.34) | 0.66 | 0.05 |
Protein EpiScores considered protective factor | |||||
LY9 | 0.79 (0.69–0.92) | 0.61 | 0.80 (0.70–0.93) | 0.65 | 0.03 |
NCAM1 | 0.77 (0.67–0.87) | 0.62 | 0.78 (0.67–0.90) | 0.65 | 0.03 |
PREP | 0.86 (0.76–0.98) | 0.60 | 0.83 (0.73–0.94) | 0.64 | 0.03 |
SEMA3E | 0.74 (0.64–0.86) | 0.62 | 0.79 (0.67–0.94) | 0.65 | 0.05 |
WFIKKN2 | 0.76 (0.67–0.87) | 0.62 | 0.80 (0.70–0.92) | 0.65 | 0.03 |