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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Glucocorticoid exposure-induced alterations in epigenetic age from human preterm infants and human lung fibroblasts and hippocampal neuronal cells

Fig. 1

Effect of antenatal corticosteroid exposure on the epigenetic age of human neonates. A Scatterplot of DNAm age estimated by the “multi-tissue predictor” from human neonate saliva (y-axis) against chronological age (x-axis). The black dashed line is the diagonal. The prediction error of DNAm age with chronological age from full-term neonates (blue circles) or preterm neonates (red triangles) is shown in panel. B, C Comparison of DNAm age between preterm neonates and full-term neonates (B) or between antenatal corticosteroid-exposed and non-exposed preterm neonates (C). D DNAm age in preterm neonates with or without exposures of antenatal magnesium sulfate (MgSO4), maternal chorioamnionitis (Chorio) or late-onset sepsis (LOS). E Linear regression analysis of the relationship between daily parenteral nutritional intake and DNAm age with R and P values. The P value derived from the Kruskal–Wallis test is shown between the indicated comparisons in the panels of B–D

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Clinical Epigenetics

ISSN: 1868-7083

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