Fig. 3

Comparison of methylation-based classification results for gliomas, glioneuronal, and neuronal tumors against initial SNUH pathological diagnoses. A DKFZ-MC v11b4 results, B SNUH-MC-91 results, and C DKFZ-MC v12.5 results. Each plot displays methylation-based classifications (right) compared to initial SNUH pathological diagnoses (left). Colors are consistent across plots and correspond to SNUH pathological diagnoses. DKFZ-MC v11b4 and SNUH-MC-91 use the same 91 methylation class labels, while DKFZ-MC v12.5 introduces new labels from its expanded 170 methylation classes. Novel tumor types in v12.5 (e.g., pedHGG, NET_PATZ1) reflect recent advances in molecular tumor classification. Detailed results are available in Supplementary Table 2 (SNUH-MC: Seoul National University Hospital-Methylation Classifier; DKFZ-MC: Deutsches Krebsforschungszentrum-Methylation Classifier)