Fig. 4
Six CpGs had different methylation change over time depending on methylation cluster. Density plot of change in methylation between visits and methylation trajectories for remission, unresolved C2, and unresolved C3 clusters for a cg08152411, b cg08888522, c cg13304609, d cg17915189, e cg05552874, and f cg02230244. These were defined as CpGs meeting all the following criteria: significant from ANOVA (p < 0.05/546), p < 0.05/411 for remission vs. unresolved C2 cluster comparison, p < 0.05/411 for unresolved C3 vs. C2 comparison, and cluster comparison coefficients were at least 50% different from each other