Table 2 The five overlapping DMCs of the top 50 ranked on delta beta and the top 50 ranked by adjusted P-value, between pleural mesothelioma (PM) and healthy pleura (PL)
CpG site | Adjusted P-value | Mean Beta in PM | Mean Beta in PL | Delta beta | Chr | Genomic location | Gene | Location gene | Location island | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
cg02515217 | 2.91E-68 | 0.121 | 0.603 |  − 0.482 | 17 | 57,918,600 | MIR21 | TSS200 | Open sea | 0.989 |
cg06249604 | 4.57E-56 | 0.727 | 0.252 | 0.475 | 6 | 30,039,206 | RNF39 | Body | Island | 0.994 |
cg15759721 | 2.82E-73 | 0.133 | 0.602 |  − 0.469 | 17 | 57,918,630 | MIR21 | Body | Open sea | 0.992 |
cg05099985 | 6.66E-60 | 0.305 | 0.768 |  − 0.462 | 1 | 16,245,931 | SPEN | Body | Open sea | 0.986 |
cg20311002 | 6.22E-55 | 0.197 | 0.649 |  − 0.452 | 1 | 244,763,541 | C1orf101 | Body | Open sea | 0.988 |