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Fig. 2 | Clinical Epigenetics

Fig. 2

From: BRCA loss of function including BRCA1 DNA-methylation, but not BRCA-unrelated homologous recombination deficiency, is associated with platinum hypersensitivity in high-grade ovarian cancer

Fig. 2

BRCA-LOF by epigenetic or genetic aberrations and survival. (A) Analysis of progression-free survival (PFS) and (B) overall survival (OS). Subgroup analyses of HRD-positive BRCA-wt-unmeth HGOC for (C) PFS and (D) OS compared with HRD-negative BRCA-wt-unmeth and with BRCA-LOF HGOC and for (E) PFS and (F) OS compared with the entire HRD-negative cohort

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Clinical Epigenetics

ISSN: 1868-7083

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