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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Integrative analysis based on ATAC-seq and RNA-seq reveals a novel oncogene PRPF3 in hepatocellular carcinoma

Fig. 3

Knockdown of PRPF3 inhibits the proliferation, migration, and invasion of liver cancer cells in vivo. A, B The knockdown efficiency of PRPF3 was confirmed in the MHCC-97 h and Huh7 cell lines using qRT-PCR(A) and western blotting(B). C CCK8 analysis of cell viability in MHCC-97 h and Huh7 cells transfected with siNC, siPRPF3-1, or siPRPF3-2. D The colony formation images of MHCC-97 h and Huh7 cells transfected with siNC, siPRPF3-1, or siPRPF3-2 on day 14. E, F EdU proliferation assay in MHCC-97 h and Huh7 cells transfected with siNC, siPRPF3-1, or siPRPF3-2. G, H Transwell assay in MHCC-97 h and Huh7 cells transfected with siNC, siPRPF3-1, or siPRPF3-2. I, J Wound healing assay in MHCC-97 h and Huh7 cells transfected with siNC, siPRPF3-1, or siPRPF3-2

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Clinical Epigenetics

ISSN: 1868-7083

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