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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Technical variability across the 450K, EPICv1, and EPICv2 DNA methylation arrays: lessons learned for clinical and longitudinal studies

Fig. 3

Pairwise comparison of epigenetic age estimates across arrays. Comparisons include the seven clocks included in the primary analyses, as well as the principal component (PC) versions of the clocks. The difference score (y-axis) represents the individual-level difference in epigenetic age estimate between two array versions, reading from left to right (e.g., 450K estimate minus EPICv1 estimate). For all clocks except DunedinPACE, the difference score reflects a difference in years of epigenetic age. For the DunedinPACE clock, the difference score reflects differences in the pace of aging

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