Table 1 Top 12 (FDR p < 10–7) independent EWAS-based CpGs associated with smoking
CpG ID | Chr | hg19 | Gene name | Gene group | p | FDR p |
|---|---|---|---|---|---|---|
cg05575921 | chr5 | 373378 | AHRR | Body | 5.95E–38 | 4.47E–32 |
cg21566642 | chr2 | 233284661 | NA | NA | 1.08E–27 | 4.05E–22 |
cg17739917 | chr17 | 38477572 | RARA | 5’UTR | 1.77E–24 | 4.44E–19 |
cg03636183 | chr19 | 17000585 | F2RL3 | Body | 1.53E–23 | 2.86E–18 |
cg14391737 | chr11 | 86513429 | PRSS23 | 5’UTR;Body | 7.14E–18 | 5.96E–13 |
cg05086879 | chr22 | 39861490 | MGAT3 | 5’UTR | 1.04E–14 | 6.02E–10 |
cg18110140 | chr15 | 75350380 | NA | NA | 6.18E–14 | 3.09E–09 |
cg19859270 | chr3 | 98251294 | GPR15 | 1stExon | 7.33E–14 | 3.44E–09 |
cg02657160 | chr3 | 98311063 | CPOX | Body | 7.32E–13 | 3.23E–08 |
cg04182427 | chr7 | 32315577 | PDE1C | Body | 1.14E–12 | 4.75E–08 |
cg09935388 | chr1 | 92947588 | GFI1 | Body | 1.28E–12 | 5.08E–08 |
cg02978227 | chr3 | 98292027 | NA | NA | 2.67E–12 | 9.56E–08 |