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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Distinct methylome profile of cfDNA in AMI patients reveals significant alteration in cAMP signaling pathway genes regulating cardiac muscle contraction

Fig. 2

Genome-wide distribution of methylation estimated from cell-free DNA and genomic DNA of AMI patients a average percentage methylation estimated from cfDNA and gDNA of AMI patients. The panel shows the mean methylation levels for cfDNA and gDNA of all samples (n = 25), b histogram for percent methylation distribution from the total cfDNA and gDNA of matched control (n = 25), c proportion of methylated regions in various genomic contexts (e.g., promoter, exon, intron) between cfDNA and gDNA, highlighting differences in methylation patterns between these two DNA sources (n = 25), d PCA plot depicting the clustering of cfDNA and gDNA methylation patterns (n = 25). Each point represents a sample, with clusters indicating similarities in methylation profiles

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Clinical Epigenetics

ISSN: 1868-7083

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