Comparison of cell type and disease subset chromatin modifications in SLE

Clinical Epigenetics

Table 1 P values of enrichment of GSEA pathways of top 500 genes with increased peak height in SLE

	Monocyte H3K4me3	Monocyte H3K27ac	Monocyte p300	B cell H3K4me3	B cell H3K27ac	B cell p300	T cell H3K4me3	T cell H3K27ac	T cell p300
TNFA signaling via NFkB	2.2X10⁻²²	2.5X10⁻¹⁴	1.9X10⁻⁹	2.2X10⁻¹⁶	3.1X10⁻¹³	3.0X10⁻¹²	2.6X10⁻⁹	3.1X10⁻¹³	-
Inflammatory response	2.2X10⁻²²	1.2X10⁻¹⁸	1.9X10⁻⁹	1.5X10⁻⁸	1.1X10⁻⁷	4.4X10⁻⁶	2.4X10⁻¹⁰	3.1X10⁻¹³	-

ISSN: 1868-7083