Skip to main content
Fig. 4 | Clinical Epigenetics

Fig. 4

From: Comparison of cell type and disease subset chromatin modifications in SLE

Fig. 4

Differential peak height in SLE versus RA. Overall, peak height is decreased in SLE compared to RA. The 20 genes (or fewer if less than 20) with the greatest significantly diminished peak heights, i.e., negative log2 fold change (log2FC), in SLE compared to RA are shown in A. Peak height (annotated by nearest gene) is ranked by the log2 fold change of the decrease and the FDR indicates the significance of the difference between lupus and RA samples for each peak as calculated in DiffBind. Volcano plots of the differentially bound peaks between SLE and RA samples are shown in B to optimally display the overall effect on peak height

Back to article page