Table 2 Clinical information of the patients in the validation cohort
From: Methylation alterations of imprinted genes in different placental diseases
Characteristics | CON (n = 99) | PAS (n = 136) | PE (n = 288) |
|---|---|---|---|
Age (years) | 32.12 ± 5.23 | 33.43 ± 4.60 | 33.26 ± 5.75 |
Gestational age (weeks) | 39.22 ± 0.89 | 36.14 ± 1.41** | 34.65 ± 3.49** |
Pre-pregnancy BMI (kg/m2) | 20.95 ± 3.26 | 21.86 ± 3.16 | 23.65 ± 4.12** |
SBP (mmHg) | 115 ± 9 | 115 ± 16 | 151 ± 18** |
DBP (mmHg) | 73 ± 7 | 72 ± 9 | 97 ± 14** |
Blood glucose (mmol/L) | 5.24 ± 1.16 | 5.30 ± 1.53 | 5.47 ± 1.64 |
Urine Protein (g/24 h) | 0 | 0.40 ± 0.31 | 2.52 ± 3.61** |
Total pregnancy | |||
 ≤ 2 | 52 (53%) | 33 (24%) | 69 (24%) |
 ≥ 3 | 47 (47%) | 103 (76%) | 219 (76%) |
Previous delivery times | |||
 ≤ 1 | 81 (82%) | 99 (73%) | 260 (90%) |
 ≥ 2 | 18 (18%) | 37 (27%) | 28 (10%) |
Number of previous cesarean sections | |||
 ≤ 1 | 84 (85%) | 114 (84%) | 274 (95%) |
 ≥ 2 | 15 (15%) | 22 (16%) | 14 (5%) |
Preterm birth | 1 (1%) | 100 (74%)** | 189 (66%)** |
Birth weight(kg) | 3.30 ± 0.33 | 2.75 ± 0.43** | 2.13 ± 0.89** |
Apgar score(10 min) | 10.00 | 9.94 ± 0.24 | 9.91 ± 0.39* |