Fig.4
From: Methylation alterations of imprinted genes in different placental diseases
Methylation levels at individual CpG sites in the DMR of the imprinted genes in the validation cohort. A KCNQ1, B MEST, C GNAS, and D IGF2.Vertical coordinates represent the methylation level, and the horizontal axis represents specific CpG sites in the analyzed DMR. M and P indicate maternal and paternal allele expression, respectively. CON, normal term controls; PAS, placenta accreta spectrum; and PE, pre-eclampsia. Data are represented as the mean ± SEM; *P < 0.05 and #P < 0.01