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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

Fig. 3

The impact of SIRT6 OE on H4 acetylation profile. Differences in A global acetylation of H4G4KGGKGLGKGGAKR17 (H4G4 − R17) peptides in control AdiE, and SIRT6 OE-samples (AdiWT and AdiCent) with a detailed view B on the levels of identified histone marks. Numbers correspond to the median values (n = 3–4) of precursor peak areas in percentages. For each histone mark, different letters indicate significant differences between AdiE, AdiWT and AdiCent according to the Student t test at p < 0.055

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