Fig. 1

Identification of colon cancer-specific hypermethylated (CaSH) regions. A Schematic diagram of the definition of the CaSH regions. B Examples of the CaSH region extended 1Â kb upstream/downstream on chr16. Dashed lines indicate start and end position of the CaSH region. C Gene set enrichment analysis of the CaSH regions. D An in silico simulation of quantification of ctDNA method, ctCandi