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Table 1 Patients’ demographical and clinical characteristics

From: Unraveling epigenomic signatures and effectiveness of electroconvulsive therapy in treatment-resistant depression patients: a prospective longitudinal study

 

Whole cohort

(n = 32)

Responders

(n = 23)

Non-responders

(n = 9)

Age in years, mean (SD)

56.9 (± 14.3)

56.9 (± 15.5)

57.0 (± 11.5)

Gender, n (% F)

22 (68.7)

18 (78.2)

4 (44.5)

Education in years, mean (SD)

8.0 (± 2.9)

8.0 (± 3.1)

8.6 (± 2.3)

BMI, mean (SD)

26.8 (± 5.3)

27.0 (± 5.8)

27.1 (± 4.0)

Smokers, n (%)

10 (31.2)

7 (30.4)

3 (33.4)

MADRS at T0, mean (SD)

33.4 (± 7.4)

33.0 (± 7.2)

34.1 (± 8.7)

MADRS at T1, mean (SD)

11.0 (± 10.0)

5.5 (± 3.9)

25.0 (± 6.1)

Delta% MADRS at T1, mean (SD)

65.9 (± 29.6)

82.2 (± 11.8)

24.2 (± 17.5)

Psychotic symptoms, n (%)

23 (71.8)

16 (69.5)

7 (77.8)

Recurrent MDD, n (%)

29 (90.6)

20 (86.9)

9 (100)

Comorbidity with personality disorders, n (%)

6 (18.8)

3 (33.3)

3 (13.0)

Comorbidity with anxiety disorders, n (%)

3 (9.4)

3 (13.0)

0 (0.0)

ECT sessions, mean (SD)

7.4 (2.2)

7.0 (1.7)

8.2 (3.2)

  1. Note: BMI: body mass index, ECT: electroconvulsive therapy, F: females, MADRS: Montgomery–Åsberg depression rating scale, MDD: major depressive disorder, SD: standard deviation