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Fig. 1 | Clinical Epigenetics

Fig. 1

From: PAX1 methylation as a robust predictor: developing and validating a nomogram for assessing endocervical curettage (ECC) necessity in human papillomavirus16/18-positive women undergoing colposcopy

Fig. 1

Flowchart of patients. CDB, colposcopically directed biopsy; ECC, endocervical curettage; PAX1, paired boxed gene 1; HPV16/18, human papillomavirus 16/18; LSIL, low-grade squamous intraepithelial lesion; HSIL + , high-grade squamous intraepithelial lesion or worse; ECC ≤ CDB, cases with pathological findings detected by ECC were less severe than or equal to CDB; ECC (H +) > CDB, cases with the pathological findings detected by ECC were more severe than CDB, with ECC detecting HSIL and worse; ECC (L) > CDB, cases in which pathological findings identified by ECC were more severe than CDB, with ECC detecting LSIL, PAX1 methylation test time apart from biopsy time greater than 2 weeks was defined as too far

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Clinical Epigenetics

ISSN: 1868-7083

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