Fig. 5

Differentially methylated regions in patients with poor stroke outcome. Region plots showing the four significant DMRs associated with stroke outcome in the meta-analysis (Q-value < 0.05). Each dot represents one CpG conforming the region. The Y-axis corresponds to the -log10 p-value and the X-axis to the CpG location. The dot color corresponds to the correlation of each CpG with the most significant CpG of each region (red indicates a positive correlation, while blue an inverse correlation). At the bottom of each plot there is the correlation matrix of the methylation levels of those CpGs conforming the region