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Fig. 3 | Clinical Epigenetics

Fig. 3

From: DNA methylation and stroke prognosis: an epigenome-wide association study

Fig. 3

Differentially methylated positions. A Bar plots showing the proportion of hyper- and hypomethylated CpGs in patients with poor outcome by CpG statistical significance (10–5). B Localization of CpGs by statistical significance (10–5). C Results obtained in the replication phase in the subset of nominally significant CpG. Dots correspond to β-coefficients and error bars to 95% confidence interval. Blue CpGs are those significant candidates after correcting for multiple testing. D Dots represent marginal means of multivariate models interrogating the association between methylation at these sites and stroke outcome for both discovery and replication studies. Error bars correspond to 99% confidence interval

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