Fig. 6

Effect of siSOS1 on the CSLC characteristics of H460-derived LCSLCs A DNMT1 activity; B DNMT1 mRNA and protein expression; C miR-152-3p levels; D SOS1 mRNA and protein levels; E Rates of sphere and colony formation (scale bar, 100 μm); F, G Expression levels of CD44, CD133, Oct4, and Sox2. All experiments were conducted in triplicate. *p < 0.05 vs. NC