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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Identification of DNA methylation biomarkers for evaluating cardiovascular disease risk from epigenome profiles altered by low-dose ionizing radiation

Fig. 2

Genome-wide differentially methylated regions in irradiated HAECs and HCAECs. A, B Genome-wide DNA methylation levels were compared between irradiated HAECs and HCAECs and control using the HumanMethylationEPIC BeadChip platform. A total of 1064 (HAECs) and 483 (HCAECs) CpG sites were hypermethylated, whereas 392 (HAECs) and 573 (HCAECs) CpG sites were hypomethylated. P values were calculated using the Mann–Whitney U test. The pie chart illustrates the distribution of genome-wide coverage among differentially methylated regions. The promoter, intergenic region, gene body, exons, and other regions are shown

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Clinical Epigenetics

ISSN: 1868-7083

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