Fig. 3

Global histone modification analysis in HeLa cells. A H4 acetylation in control cells (top) and in BPA-exposed cells (bottom); B Quantitative analysis of H4 acetylation; C H3K9me3 in control cells (top) and in BPA-exposed cells (bottom); D Quantitative analysis of H3K9me3. The sum of fluorescence for all slices of z-stacks was calculated for each channel. The histone modification signal was normalized to DAPI and presented as combined corrected fluorescence compared to the control, *p < 0.05, Mann‒Whitney test, n = 4 experiments for each group