Skip to main content
Fig. 6 | Clinical Epigenetics

Fig. 6

From: Identification of DNA methylation-regulated genes as potential biomarkers for coronary heart disease via machine learning in the Framingham Heart Study

Fig. 6

Feature importance in the LightGBM-based machine learning models and validation of hub genes in peripheral blood monocytes. A–C Feature importance in the methylation model, expression model and combination model quantized by Gini importance. D-F Feature importance in the methylation model, expression model and combination model based on SHAP values. G, H Methylation and expression levels of the five hub genes in monocytes from CHD patients and controls. I-K PCA plots based on the methylation data, expression data, integrated methylation and expression data of the five hub genes in monocytes from CHD patients and controls

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us