Fig. 1

Methylation and expression patterns in the training set of FHS. A Locations of DMPs on chromosomes. Hypermethylated and hypomethylated DMPs in CHD were marked in red and blue, respectively. B, C Distributions of DMPs in various gene regions. D UpSet plot for DMPs in various gene regions. E DMPs distribution in TSS regions of each chromosome. F DMPs distribution in TSS1500. G DMPs distribution in TSS200. H–J GO, KEGG and Reactome enrichment results in GSEA based on the transcriptome data of all genes