Fig. 6

PDCD5 regulates the HDAC3/miR-195-5p/SGK1 axis to inhibit in vivo tumorigenicity of RCC cells. A Representative images of resected tumors. B Tumor weight. C Tumor volume. D mRNA expression of PDCD5 in the tumor tissues of nude mice determined by RT-qPCR. E mRNA expression of HDAC3 in the tumor tissues of nude mice determined by RT-qPCR. F miR-195-5p expression in the tumor tissues of nude mice determined by RT-qPCR. G mRNA expression of SGK1 in the tumor tissues of nude mice determined by RT-qPCR. H, IFN-γ⁺ T cell proportion detected by flow cytometry. I The expression of IFN-γ released from CD3⁺ T cells determined by ELISA. n = 8. *p < 0.05 between the two groups. The results were measurement data and expressed as mean ± standard deviation