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Fig. 7 | Clinical Epigenetics

Fig. 7

From: Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis

Fig. 7

MEF2C-AS1 expression levels in different cell lines and its functional role in cell proliferation, migration, and invasion in CRC cells. a The difference of MEF2C-AS1 expression between normal colonic cell line and CRC cell lines. b MEF2C-AS1 expression in RKO cells treated with different concentrations of demethylation agent 5-Aza-dC. c Transfection efficiency of MEF2C-AS1 overexpression plasmid in RKO cells. The cells in the control group are treated with empty vectors. d Cell viability assay. e Wound healing assay. f Transwell migration assay. g Transwell invasion assay. 5-Aza-dC, 5-aza-2’-deoxycytidine; CRC, colorectal cancer. ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05

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Clinical Epigenetics

ISSN: 1868-7083

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