Fig. 4

MEF2C-AS1 hypermethylation among patients at all stages during colorectal carcinogenesis in in-house step 3. a NAA patients. b AA patients. c CRC patients. Line chart presents the methylation level of each individual CpG site. The distribution of the mean methylation level of all individual CpG sites is shown in the scatter plot. Pie chart presents the percentage of patients with hypermethylation or hypomethylation status. AA, advanced adenoma; CRC, colorectal cancer; NAA, non-advanced adenoma. ***p < 0.001