Fig. 1

The DNA methylation biomarker set differentiates between pancreatic adenocarcinoma and benign pancreatic disease with high sensitivity and specificity. A Mean DNA methylation signal per marker for the control group of 44 patients with benign pancreatic disease and for the group of 19 pancreatic ductal adenocarcinoma cases. The y-axis is in a log2 scale. p = 6.5 × 10–16 by Wilcoxon rank sum test. B The receiver operating characteristic (ROC) analysis of the biomarker set signal from 44 controls and 19 cancer cases. AUC area under the curve, CI confidence interval