Fig. 1

Whole gene methylation analysis of UNC5 receptors in TCGA dataset of CRC. Whole gene methylation analysis of UNC5 receptors in TCGA dataset of CRC using Methylation Plotter. Based on the 450Â K array data in TCGA database, the mean methylation levels (beta values) of CpG sites across each gene in CRC (red) and paired normal tissues (blue) were calculated. Representation of individual receptor, A UNC5A, B UNC5B, C UNC5C, D UNC5D. Chromosome location of each receptor was as indicated. TSS, transcription start site