Fig. 3

Methylation level and time free from CRC. Percentage of patients who had not developed CRC is reported on Y-axis, whereas on X-axis time is represented in months. Gray curve shows patients with hypomethylated adenomas, and black curve displays patients with non-hypomethylated adenomas. a Hypomethylation was assessed when at least one of the two assays was below 60%. b Hypomethylation according to only the LINE-1 assay below 60%. c Hypomethylation according to only the L1-MET assay below 60%