Fig. 3

Risk factor-module relationships. a Pearson correlations between a series of traditional cardiovascular risk factors and module eigenCpGs (blue and brown) are shown in each study population. b Pearson correlations between historical risk factor levels in FHS (across previous exams, x-axis) and current brown module activation are shown. Gray panels indicate that the risk factor in question was not available for the corresponding exam (LDL and hsCRP) or was not analyzed with respect to past exams (smoking and age)