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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA hypomethylation of a transcription factor binding site within the promoter of a gout risk gene NRBP1 upregulates its expression by inhibition of TFAP2A binding

Fig. 2

NRBP1 is overexpressed in PBMCs from gout patients. a Relative NRBP1 mRNA expression in freshly isolated PBMCs from 15 gout patients and 17 healthy controls detected by quantitative real-time PCR (qPCR). The expression level of NRBP1 is normalized to GAPDH and is represented as mean ± SEM. (P value = 0.004, Student’s t test, unpaired, two-sided). b NRBP1 protein expression in freshly isolated PMBCs from 7 gout patients and healthy controls detected by Western blotting

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Clinical Epigenetics

ISSN: 1868-7083

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