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Fig. 1 | Clinical Epigenetics

Fig. 1

From: MeCP2 and the enigmatic organization of brain chromatin. Implications for depression and cocaine addiction

Fig. 1

a Gene organization of MeCP2. Two isoforms E1 and E2 result from alternative splicing. The red arrows indicate the starting sites of transcription. The domain organization of the resulting protein isoforms is also shown. CTD; C-terminal domain; ID: intervening domain; MBD: methyl-binding domain; NTD; N-terminal domain; TRD: transcriptional repression domain. b Number of publications since MeCP2 was first described

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Clinical Epigenetics

ISSN: 1868-7083

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